REYE SYNDROME

Question 1

What is  REYE SYNDROME?

Accepted Answer

Reye syndrome (RS) is an acute metabolic encephalopathy and hepatopathy affecting children and adolescents,
a specific underlying defect should be excluded by careful clinical and biochemical investigation risk factors: acetylsalicylic acid, phenothiazines, anti-emetics

Question 2

Gibt es eine deutsche Bezeichnung?

Accepted Answer

Reye-Syndrom

Question 3

Which enzymes are involved?

Accepted Answer

unknown

Disease	REYE SYNDROME
Orphanet	3096
Gene locus	unknown
ICD	G93.7
Summary	Reye syndrome (RS) is an acute metabolic encephalopathy and hepatopathy affecting children and adolescents, a specific underlying defect should be excluded by careful clinical and biochemical investigation risk factors: acetylsalicylic acid, phenothiazines, anti-emetics
Laboratory findings	Ammonia inc (blood) Creatine kinase inc (serum) D-Glucose dec (serum) Lactate dehydrogenase (LDH) inc (serum) pH dec (blood) Transaminases (ASAT/ALAT) normal/inc (serum)
Symptoms	Coagulopathy/Coagulation factors coma defect of deep tendon reflexes EEG abnormalities [-] encephalopathy hyperammonemia hypoglycemia lethargy, drowsiness, apathy liver involvement or dysfunction onset, adolescent onset, childhood onset, infancy pancreatitis seizures tachypnea, hyperpnea, dyspnea, hyperventilation